The country needs to be careful not to create a socioeconomically disadvantaged class of immunocompromised persons. In general, pre-COVID, such persons were well integrated into the American workforce. Until a vaccine is widely distributed, those most vulnerable to contracting COVID-19 will need to be protected in the workplace or given paid time off until those accommodations are in place or employers won't be motivated to do so. Work space distancing, PPE, and other measures are needed. The risk of cohort placement of immunocompromised persons may lead to substandard work conditions if segregation instead of workplace integration is encouraged.